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Akt/NF-κB/MAPK-IN-1
Akt/NF-κB/MAPK-IN-1
SKU:QM-0068411
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Quantity
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Product Details
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Description
Akt/NF-κB/MAPK-IN-1 (compound 2m) is a potent and orally active inhibitor against NO (IC50=7.70 μM) with no significant toxicity. Akt/NF-κB/MAPK-IN-1 shows anti-inflammatory activity by inhibiting Akt/NF-κB and MAPK signaling pathways[1].
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Molecular Formula
C38H56N2O4
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Molecular Weight
604.86
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Smiles
O[C@@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@@](CC3)([H])[C@H](C)CCC(N4CCN(CC4)C(/C=C/C5=CC=C(C=C5)C)=O)=O)(CC[C@]2([H])[C@@]6([C@](C[C@@H](CC6)O)([H])C1)C)C
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Target
COX; ERK; Interleukin Related; JNK; NO Synthase; p38 MAPK; TNF Receptor
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Isoform
COX-2; IL-1; IL-6; iNOS
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Akt/NF-κB/MAPK-IN-1
Akt/NF-κB/MAPK-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.