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Akt1/Akt2-IN-2 [CAS 612847-42-4]
Akt1/Akt2-IN-2 [CAS 612847-42-4]
SKU:QM-0061196
£250.47 GBP
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Product Details
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Description
Akt1/Akt2-IN-2 (compound 7) is an allosteric dual Akt1 and Akt2 inhibitor (IC50=138 nM and 212 nM, respectively) . Akt1/Akt2-IN-2 increases activity of caspase-3, and inhibits viability of a number of tumor cells[1].
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CAS Number
[612847-42-4]
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Molecular Formula
C40H43N7O2
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Molecular Weight
653.82
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Smiles
O=C(C1=CC=C2N=C(C3=CC=CC=C3)C(C4=CC=C(CN5CCC(N6C7=CC=CC=C7NC6=O)CC5)C=C4)=NC2=C1)NCCN(CC)CC
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Target
Akt; Caspase
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Isoform
Akt1; Akt2; Akt3; Caspase 3
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Purity
98.57
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Solubility
DMSO : 125 mg/mL (ultrasonic) |H2O : 18 mg/mL (ultrasonic; warming)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Akt1/Akt2-IN-2 [CAS 612847-42-4]
Akt1/Akt2-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.