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AKT1-IN-11 [CAS 3087064-94-3]
AKT1-IN-11 [CAS 3087064-94-3]
SKU:QM-0016081
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Product Details
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Description
AKT1-IN-11, a Podophyllotoxin derivative, is a AKT1/tubulin dual inhibitor. AKT1-IN-11 down-regulates the phosphorylation level of AKT kinase in tumor cells, disrupting cell proliferation, causeing G2/M phase arrest and inducing apoptosis. AKT1-IN-11 also promotes tubulin depolymerization. AKT1-IN-11 can be used for the research of colorectal cancer[1].
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CAS Number
[3087064-94-3]
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Molecular Formula
C33H32N4O11S
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Molecular Weight
692.69
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Smiles
COC1=C(OC)C(OC)=CC([C@H]2[C@]3([H])[C@@](COC3=O)([H])[C@@H](OCC4=CN(S(C5=CC=C(NC(C)=O)C=C5)(=O)=O)N=N4)C6=CC7=C(OCO7)C=C26)=C1
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Target
Akt; Apoptosis; Microtubule/Tubulin
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Shipping Conditions
Room temperature
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AKT1-IN-11 [CAS 3087064-94-3]
AKT1-IN-11 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.