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Akt3 degrader 1 [CAS 2836342-69-7]
Akt3 degrader 1 [CAS 2836342-69-7]
SKU:QM-0069479-01
£499.55 GBP
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Product Details
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Description
Akt3 degrader 1 (compound 12l) is a selective Akt3 degrader that overcomesOsimertinib -induced resistance in H1975OR NSCLC cells. Akt3 degrader 1 also has anti-proliferative activity and significantly inhibits tumour growth in mice. Akt3 degrader 1 can be used in the study of drug-resistant non-small cell lung cancer[1].
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CAS Number
[2836342-69-7]
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Molecular Formula
C53H72N8O4
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Molecular Weight
885.19
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Smiles
COC1=C(C=CC(N2CCN(CC2)CCCCCCCCCCCCNC(CC34CC5CC(C4)CC(C3)C5)=O)=C1)NC6=NC=C7C(C)=CC(N(C7=N6)C8=CC=CC(NC(C9CC9)=O)=C8)=O
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Target
Akt
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Purity
99.43
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Akt3 degrader 1 [CAS 2836342-69-7]
Akt3 degrader 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.