AKTide-2T (TFA)
AKTide-2T (TFA)
SKU:QM-0084123
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Product Details
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Description
AKTide-2T TFA is an excellent in vitro substrate for AKT and shows competitive inhibition of histone H2B phosphorylation with a Ki of 12 nM. AKTide-2T TFA mimics the optimal phosphorylation sequence of Akt and is an inhibitory peptide with the wildtype AKTide lacking Thr in the S22 position[1].
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Molecular Formula
C74H114N28O20.xC2HF3O2
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Smiles
OC(C(F)(F)F)=O.O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CO)C(N[C@@H](CC2=CC=CC=C2)C(NCC(N[C@@H](CC3=CNC=N3)C(N[C@@H](CC4=CNC=N4)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N
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Target
Akt
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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AKTide-2T (TFA)
AKTide-2T (TFA) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.