Alectinib (Hydrochloride) [CAS 1256589-74-8]

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SKU:QM-0143062-01

£78.82 GBP

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Product Details

Description
Alectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively[1]. Alectinib demonstrates effective central nervous system (CNS) penetration[2].
CAS Number
[1256589-74-8]
Molecular Formula
C30H35ClN4O2
Molecular Weight
519.08
Smiles
[H]Cl.N#CC1=CC2=C(C3=C(N2)C(C)(C4=CC(N5CCC(CC5)N6CCOCC6)=C(C=C4C3=O)CC)C)C=C1
Target
Anaplastic lymphoma kinase (ALK)
Purity
99.92
Solubility
DMSO : 2 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Shipping Conditions
Room Temperature
Hazard Statement
H341, H361, H373
Precautions
H341, H361, H373

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0143062-01	5 mgQM-0143062-01 £78.82/ea	£0.00	Quantity	£78.82/ea	£0.00

10 mgQM-0143062-02	10 mgQM-0143062-02 £102.63/ea	£0.00	Quantity	£102.63/ea	£0.00

25 mgQM-0143062-03	25 mgQM-0143062-03 £131.88/ea	£0.00	Quantity	£131.88/ea	£0.00

50 mgQM-0143062-04	50 mgQM-0143062-04 £200.66/ea	£0.00	Quantity	£200.66/ea	£0.00

100 mgQM-0143062-05	100 mgQM-0143062-05 £290.57/ea	£0.00	Quantity	£290.57/ea	£0.00

200 mgQM-0143062-06	200 mgQM-0143062-06 £441.23/ea	£0.00	Quantity	£441.23/ea	£0.00

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Alectinib (Hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.