Alectinib (Hydrochloride) (Standard) [CAS 1256589-74-8]
Alectinib (Hydrochloride) (Standard) [CAS 1256589-74-8]
SKU:QM-0005616-01
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Product Details
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Description
Alectinib (Hydrochloride) (Standard) is the analytical standard of Alectinib (Hydrochloride) . This product is intended for research and analytical applications. Alectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively[1]. Alectinib demonstrates effective central nervous system (CNS) penetration[2].
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CAS Number
[1256589-74-8]
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Molecular Formula
C30H35ClN4O2
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Molecular Weight
519.08
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Smiles
[H]Cl.N#CC1=CC2=C(C3=C(N2)C(C)(C4=CC(N5CCC(CC5)N6CCOCC6)=C(C=C4C3=O)CC)C)C=C1
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Target
Anaplastic lymphoma kinase (ALK) ; Reference Standards
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Purity
99.8
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Storage Conditions
4°C, sealed storage, away from light and moisture
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Shipping Conditions
Blue Ice
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Hazard Statement
H341, H361, H373
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Precautions
H341, H361, H373
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Alectinib (Hydrochloride) (Standard) [CAS 1256589-74-8]
Alectinib (Hydrochloride) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.