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Alicapistat [CAS 1254698-46-8]
Alicapistat [CAS 1254698-46-8]
SKU:QM-0136327-01
£991.63 GBP
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Product Details
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Description
Alicapistat (ABT-957) is an orally active selective inhibitor of human calpains 1 and 2 for the potential application of Alzheimer's disease (AD) [1]. Alicapistat mitigates the metabolic liability of carbonyl reduction and inhibits calpain 1 with an IC50 value of 395 nM[2].
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CAS Number
[1254698-46-8]
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Molecular Formula
C25H27N3O4
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Molecular Weight
433.5
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Smiles
O=C1N([C@H](CC1)C(NC(C(C(NC2CC2)=O)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4
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Target
Proteasome
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Purity
98
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Alicapistat [CAS 1254698-46-8]
Alicapistat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.