ALKBH1-IN-3 prodrug [CAS 3056005-98-9]
ALKBH1-IN-3 prodrug [CAS 3056005-98-9]
SKU:QM-0082885-01
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Product Details
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Description
ALKBH1-IN-4 prodrug (Compound 29E) is a prodrug of a DNA N6-methyladenine demethylase ALKBH1 inhibitor that significantly increases the abundance of 6mA in cells and upregulates the AMPK signaling pathway, thereby inhibiting the viability of gastric cancer cells. ALKBH1-IN-4 prodrug exhibits excellent cellular activity and favorable metabolic exposure in vivo, and holds promise for research in gastric cancer[1].
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CAS Number
[3056005-98-9]
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Molecular Formula
C18H18N4O4
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Molecular Weight
354.36
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Smiles
O=C(C1=CN(C2=NC=C(C=N2)OCC3=CC(OC)=CC=C3)N=C1)OCC
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Target
AMPK
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Purity
99.15
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Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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ALKBH1-IN-3 prodrug [CAS 3056005-98-9]
ALKBH1-IN-3 prodrug is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.