Alkyne-phenol [CAS 1694495-59-4]
Alkyne-phenol [CAS 1694495-59-4]
SKU:QM-0143645-01
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Product Details
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Description
Alkyne-phenol (Alk-Ph) is a clickable ascorbate peroxidase 2 (APEX2) probe. Alkyne-phenol substantially improves APEX-labeling efficiency in intact yeast cells, as it is more cell wall-permeant than APEX2 substrate biotin-phenol (BP) . Alkyne-phenol also facilitates the identification of APEX-labeling sites, allowing the unambiguous assignment of membrane topology of mitochondrial proteins[1]. Alkyne-phenol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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CAS Number
[1694495-59-4]
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Molecular Formula
C13H15NO2
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Molecular Weight
217.26
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Smiles
C#CCCC(NCCC1=CC=C(O)C=C1)=O
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Target
Biochemical Assay Reagents
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Concentration
10mM
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Purity
99.72
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Solubility
DMSO : 50 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Alkyne-phenol [CAS 1694495-59-4]
Alkyne-phenol is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.