Alrizomadlin (Standard) [CAS 1818393-16-6]
Alrizomadlin (Standard) [CAS 1818393-16-6]
SKU:QM-0002421
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Product Details
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Description
Alrizomadlin (Standard) is the analytical standard of Alrizomadlin. This product is intended for research and analytical applications. Alrizomadlin (APG-115) is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC50 and Ki values of 3.8 nM and 1 nM, respectively[1]. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner[2][3].
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CAS Number
[1818393-16-6]
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Molecular Formula
C34H38Cl2FN3O4
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Molecular Weight
642.59
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Smiles
O=C(N1)[C@]([C@@H](C(C=CC=C2Cl)=C2F)[C@@H]3C(NC45CCC(C(O)=O)(CC5)CC4)=O)(C(C1=C6)=CC=C6Cl)C7(CCCCC7)N3CC
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Target
Apoptosis; E1/E2/E3 Enzyme; MDM-2/p53; Reference Standards
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Shipping Conditions
Room temperature
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Alrizomadlin (Standard) [CAS 1818393-16-6]
Alrizomadlin (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.