AMD 3465 (hexahydrobromide) (Standard) [CAS 185991-07-5]
AMD 3465 (hexahydrobromide) (Standard) [CAS 185991-07-5]
SKU:QM-0007926-01
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Product Details
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Description
AMD 3465 (hexahydrobromide) (Standard) is the analytical standard of AMD 3465 (hexahydrobromide) . This product is intended for research and analytical applications. AMD 3465 hexahydrobromide (GENZ-644494 hexahydrobromide) is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM), but has no effect on CCR5-using (R5) viruses.
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CAS Number
[185991-07-5]
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Molecular Formula
C24H44Br6N6
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Molecular Weight
896.07
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Smiles
[H]Br.[H]Br.[H]Br.[H]Br.[H]Br.[H]Br.C1(CNCC2=CC=C(CN3CCNCCCNCCNCCC3)C=C2)=NC=CC=C1
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Target
CXCR; HIV; Reference Standards
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Shipping Conditions
Room temperature
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AMD 3465 (hexahydrobromide) (Standard) [CAS 185991-07-5]
AMD 3465 (hexahydrobromide) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.