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AMI-1 (free acid) [CAS 134-47-4]
AMI-1 (free acid) [CAS 134-47-4]
SKU:QM-0155189-01
£51.91 GBP
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Product Details
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Description
AMI-1 free acid is a potent, cell-permeable and reversible inhibitor of protein arginine N-methyltransferases (PRMTs), with IC50s of 8.8 μM and 3.0 μM for human PRMT1 and yeast-Hmt1p, respectively. AMI-1 free acid exerts PRMTs inhibitory effects by blocking peptide-substrate binding[1].
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CAS Number
[134-47-4]
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Molecular Formula
C21H16N2O9S2
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Molecular Weight
504.49
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Smiles
O=C(NC1=CC2=CC(S(=O)(O)=O)=CC(O)=C2C=C1)NC3=CC4=CC(S(=O)(O)=O)=CC(O)=C4C=C3
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Target
Histone Methyltransferase
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Isoform
PRMT1
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Purity
99.53
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Solubility
DMSO : 83.33 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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AMI-1 (free acid) [CAS 134-47-4]
AMI-1 (free acid) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.