(Aminooxy) acetamide-Val-Cit-PAB-MMAE [CAS 2446645-88-9]
(Aminooxy) acetamide-Val-Cit-PAB-MMAE [CAS 2446645-88-9]
SKU:QM-0151084-01
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Product Details
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Description
(Aminooxy) acetamide-Val-Cit-PAB-MMAE (MMAE 5) is an intermediate used in the synthetic preparation of drug-linker conjugates for ADC. (Aminooxy) acetamide-Val-Cit-PAB-MMAE is conjugated to polyamide via oxime bond formation to form MMAE polyamide conjugate. Then MMAE polyamide conjugate can be conjugated to Trastuzumab, to make ADC[1].
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CAS Number
[2446645-88-9]
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Molecular Formula
C60H97N11O14
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Molecular Weight
1196.48
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Smiles
C[C@@H](C(N[C@H](C)[C@H](C1=CC=CC=C1)O)=O)[C@H]([C@@](CCC2)([H])N2C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC(C=C3)=CC=C3NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CON)=O)=O)=O)=O)=O)=O)=O)OC
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Target
Drug-Linker Conjugates for ADC
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Purity
96.87
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Blue Ice
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(Aminooxy) acetamide-Val-Cit-PAB-MMAE [CAS 2446645-88-9]
(Aminooxy) acetamide-Val-Cit-PAB-MMAE is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.