Amitriptyline-d3 (hydrochloride) [CAS 342611-00-1]
Amitriptyline-d3 (hydrochloride) [CAS 342611-00-1]
SKU:QM-0144948-01
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Product Details
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Description
Amitriptyline-d3 hydrochloride is the deuterium labeled Amitriptyline (hydrochloride) . Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET), with Kis of 3.45 nM and 13.3 nM for human SERT and NET, respectively. Amitriptyline hydrochloride also weakly binds to dopamine reuptake transporter (DAT) with a Ki of 2.58 μM. Amitriptyline hydrochloride also inhibits adrenergic, muscarinic, histamine and 5-HT receptors. Amitriptyline hydrochloride is a TrkA and TrkB receptors agonist with potent neurotrophic activity. Amitriptyline hydrochloride has antidepressant activity[1][2][3].
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CAS Number
[342611-00-1]
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Molecular Formula
C20H21D3ClN
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Molecular Weight
316.88
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Smiles
[2H]C(N(C)CC/C=C1C2=CC=CC=C2CCC3=CC=CC=C\13)([2H])[2H].[H]Cl
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Target
5-HT Receptor; Adrenergic Receptor; Histamine Receptor; mAChR; Serotonin Transporter; Sodium Channel; Trk Receptor
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Purity
99.46
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Solubility
H2O : 50 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H225-H301+H311+H331-H370
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Precautions
P210-P233-P240-P241-P242-P243-P260-P261-P264-P270-P271-P280-P302+P352-P303+P361+P353-P304+P340-P308+P311-P330-P361+P364-P370+P378-P403+P233-P403+P235-P405-P501
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Amitriptyline-d3 (hydrochloride) [CAS 342611-00-1]
Amitriptyline-d3 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.