Anagrelide-13C2,15N, d2
Anagrelide-13C2,15N, d2
SKU:QM-0118583
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Product Details
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Description
Anagrelide-13C2,15N, d2 is 15N and deuterated labeled Anagrelide. Anagrelide is a potent inhibitor of phosphodiesterase type III (PDE3) (IC50=36 nM). Anagrelide, an imidazoquinazoline derivative, acts as an inhibitor of platelet aggregation. Anagrelide inhibits bone marrow megakaryocytopoiesis. Anagrelide decreases gastrointestinal stromal tumor (GIST) cell proliferation and promotes their apoptosis in vitro. Anagrelide is a platelet-lowering agent and plays in the antithrombopoietic action[1][2][3].
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Molecular Formula
C9 13C2H8D2Cl2N 15NO
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Molecular Weight
262.11
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Smiles
O=[13C]1CC2NC3=C(C(Cl)=C(Cl)C=C3)C([2H])([2H])[15N]2[13CH2]1
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Target
Apoptosis; Isotope-Labeled Compounds; Phosphodiesterase (PDE)
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Anagrelide-13C2,15N, d2
Anagrelide-13C2,15N, d2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.