Antalarmin (hydrochloride) [CAS 220953-69-5]
Antalarmin (hydrochloride) [CAS 220953-69-5]
SKU:QM-0083252-01
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Product Details
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Description
Antalarmin (hydrochloride) is an oral active non-peptide corticotropin-releasing hormone receptor 1 (CRHR1) antagonist with a Ki of 1 nM. Antalarmin hydrochloride suppresses CRH-induced ACTH secretion and blocks CRH and novelty induced anxiety-like behavior in animal models. Antalarmin hydrochloride produces anti-inflammatory effects in arthritis models, and suppresses stress-induced gastric ulceration related to irritable bowel syndrome[1][2][3].
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CAS Number
[220953-69-5]
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Molecular Formula
C24H35ClN4
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Molecular Weight
415.01
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Smiles
CC1=C(N2C(C)=C(C)C3=C(N(CCCC)CC)N=C(C)N=C32)C(C)=CC(C)=C1.[H]Cl
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Target
CRFR
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Purity
99.87
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Solubility
DMF : 20 mg/mL (ultrasonic; warming) |DMSO : 125 mg/mL (ultrasonic) |Ethanol : 14 mg/mL (ultrasonic; warming)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Antalarmin (hydrochloride) [CAS 220953-69-5]
Antalarmin (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.