Antazoline (hydrochloride) [CAS 2508-72-7]
Antazoline (hydrochloride) [CAS 2508-72-7]
SKU:QM-0159314-01
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Product Details
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Description
Antazoline hydrochloride is a histamine H1 receptor antagonist with anticholinergic and antiviral properties. Antazoline hydrochloride can prevent histamine from acting on target cells through a reversible competition effect on histamine receptor sites of these cells. Antazoline hydrochloride can exert an antiallegic effect and prevent the occurrence of physiological reactions from the effect of blocking as well as inhibiting H1 receptor. Antazoline hydrochloride can effectively reduce HBV DNA in the extracellular supernatant in a dose-dependent manner, with EC50 of 2.910 μmol/L in HepAD38 cells. Antazoline hydrochloride also has a significant inhibitory effect on HBV DNA in the extracellular supernatant of Huh7 cells (EC50 = 2.349 μmol/L) . Antazoline hydrochloride has anti-arrhythmic effect in acute myocardial infarctions. Antazoline hydrochloride can be studied in research for cardiovascular diseases, and HBV[1][2][3].
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CAS Number
[2508-72-7]
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Molecular Formula
C17H20ClN3
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Molecular Weight
301.81
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Smiles
[H]Cl.C1(CN(C2=CC=CC=C2)CC3=CC=CC=C3)=NCCN1
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Target
HBV; Histamine Receptor
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Purity
99.7
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Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302+H312+H332, H315, H319, H335
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Precautions
H302+H312+H332, H315, H319, H335
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Antazoline (hydrochloride) [CAS 2508-72-7]
Antazoline (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.