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Anticancer agent 109 [CAS 2097497-16-8]
Anticancer agent 109 [CAS 2097497-16-8]
SKU:QM-0068164
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Product Details
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Description
Anticancer agent 109 (compound 6-15) is an inhibitor of the Gas6-Axl axis with anti-cancer activity. Anticancer agent 109 inhibits the expression of Gas6 and Axl, and the expression p-PI3K and p-AKT in cancer cells, leads to G1 phase arrest and promotes cancer cells apoptosis, and inhibits tumor growth significantly in nude mouse tumor bearing models[1].
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CAS Number
[2097497-16-8]
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Molecular Formula
C19H15N3O2
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Molecular Weight
317.34
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Smiles
O=C(/C(C1=C2C)=C\C3=NC4=C(C=CC=C4)C=C3)NC1=NC(C)=C2O
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Target
TAM Receptor
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Isoform
Axl
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Anticancer agent 109 [CAS 2097497-16-8]
Anticancer agent 109 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.