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Anticancer agent 164 [CAS 2235393-30-1]
Anticancer agent 164 [CAS 2235393-30-1]
SKU:QM-0061103
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Product Details
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Description
CML-IN-1 (compound 7) is a potent anticancer agent. CML-IN-1 displays very good induced-apoptosis effect for human chronic myeloid leukemia (CML) cell line K562. CML-IN-1 exerts its effect via a significantly reduced protein phosphorylation of PI3K/Akt signal pathway. CML-IN-1 (compound 4) also inhibits cell proliferation by suppressing the MEK/ERK signaling pathway in colorectal cancer[1][2].
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CAS Number
[2235393-30-1]
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Molecular Formula
C21H23F3N8O2S2
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Molecular Weight
540.58
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Smiles
O=C(NC1=CC=C(C(F)(F)F)C=C1)NC2=NN=C(SC3=NC=NC(NCCCN4CCOCC4)=C3)S2
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Target
Apoptosis; MEK; PI3K
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Anticancer agent 164 [CAS 2235393-30-1]
Anticancer agent 164 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.