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Anticancer agent 249 [CAS 9007-83-4]
Anticancer agent 249 [CAS 9007-83-4]
SKU:QM-0115113
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Product Details
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Description
Anticancer agent 249 (Compound 89) is an inhibitor for Hsp90β with IC50 of 16.5 μM in PC3MM2 cell. Anticancer agent 249 inhibits proliferation of cancer cells MCF-7, T47D, MDA-MB-231, MDA-MB-468 and SKBr3 with IC50 of 1.8-5.3 μM. Anticancer agent 249 induces apoptosis in MDA-MB-231. Anticancer agent 249 exhibits antitumor efficacy in mice[1].
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CAS Number
[9007-83-4]
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Molecular Formula
C25H31Cl2N3O2
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Molecular Weight
476.44
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Smiles
ClC1=CC=C(NC(C2CCN(CC3=CC=C(OCC4CCNCC4)C=C3)CC2)=O)C=C1Cl
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Target
Apoptosis; HSP
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Shipping Conditions
Room temperature
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Anticancer agent 249 [CAS 9007-83-4]
Anticancer agent 249 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.