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Anticancer agent 267
Anticancer agent 267
SKU:QM-0011194
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Product Details
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Description
Anticancer agent 267 (Compound 5q) is the activator for RIPK3 and MLKL. Anticancer agent 267 inhibits the proliferation in a variety of cancer cell lines (IC50 for MDA-MB-231, MDA-MB-486 and MCF-7 is 9.79, 10.77 and 5.94 μM, respectively), arrests cell cycle at subG1 phase, and induces necroptosis in cell MDA-MB-231. Anticancer agent 267 exhibits antitumor activity in mouse xenograft models[1].
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Molecular Formula
C13H11N5O4S
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Molecular Weight
333.32
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Smiles
O=C(C(N/N=C/C1=CC=C([N+]([O-])=O)S1)=O)NCC2=CC=CC=N2
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Target
Mixed Lineage Kinase; Necroptosis; RIP kinase
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Shipping Conditions
Room temperature
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Anticancer agent 267
Anticancer agent 267 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.