Anticancer agent 273
Anticancer agent 273
SKU:QM-0010950
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Product Details
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Description
Anticancer agent 273 (Compound 9q) is a potent anticancer agent found in matrine. Anticancer agent 273 inhibits the proliferation of cancer cells (e.g., HeLa cells with an IC50 value of 4.48 μM) . Anticancer agent 273 exerts anticancer effects by modulating the expression of PI3K/AKT and activating transcription factor 4 (ATF4), which promotes endoplasmic reticulum stress and induces apoptosis. Anticancer agent 273 is promising for research of cancers, such as cervical cancer[1].
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Molecular Formula
C33H34N4O3
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Molecular Weight
534.65
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Smiles
[H][C@@]12CCCN3CCC[C@@]([C@@]31[H])([C@]4(CC/C(C(N4C2)=O)=C\OC(C5=CN(C6=C5C=CC=C6)CC7=CC=CC=C7C#N)=O)[H])[H]
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Target
Akt; Apoptosis; PI3K
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Shipping Conditions
Room temperature
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Anticancer agent 273
Anticancer agent 273 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.