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Anticancer agent 276
Anticancer agent 276
SKU:QM-0012900
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Product Details
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Description
Anticancer agent 276 (Compound 5) is a multi-target anticancer agent. Anticancer agent 276 has a potent anticancer activity against human tumor cells with IC50s of 6.90 and 4.48 μM for HEPG2 and MCF7 cells, respectively. Anticancer agent 276 shows strong and stable interactions across multiple targets, including Topoisomerase II, VEGFR2, c-Met, EGFR and ERα[1].
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Molecular Formula
C24H21N5O
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Molecular Weight
395.46
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Smiles
NN1C(C2=C(N=C1[C@H]3CC(C4=CC=CC=C4)=NN[C@H]3C5=CC=CC=C5)C=CC=C2)=O
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Target
C-Met/HGFR; EGFR; Estrogen Receptor/ERR; Topoisomerase; VEGFR
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Isoform
ERα; Topo II; VEGFR2/KDR/Flk-1
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Shipping Conditions
Room temperature
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Anticancer agent 276
Anticancer agent 276 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.