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Antitumor agent-138 [CAS 2975168-22-8]
Antitumor agent-138 [CAS 2975168-22-8]
SKU:QM-0104018
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Product Details
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Description
Antitumor agent-138 (compound 5b) is an inhibitor against tubulin polymerization at tubulin colchicine-binding sites, with IC50 of 1.87 μM. Antitumor agent-138 arrests the cell cycle at G2/M phase and induces an apoptosis in MCF-7 cells. Antitumor agent-138 inhibits cells migration and angiogenesis[1].
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CAS Number
[2975168-22-8]
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Molecular Formula
C20H21N3O4
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Molecular Weight
367.4
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Smiles
CC1=CC=C(C2=CC(N)=NN2C(C3=CC(OC)=C(OC)C(OC)=C3)=O)C=C1
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Target
Apoptosis; Microtubule/Tubulin
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Antitumor agent-138 [CAS 2975168-22-8]
Antitumor agent-138 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.