Apilimod (mesylate) [CAS 870087-36-8]
Apilimod (mesylate) [CAS 870087-36-8]
SKU:QM-0148922-01
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Product Details
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Description
Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively[1]. Apilimod is a potent and highly selective PIKfyve inhibitor.
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CAS Number
[870087-36-8]
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Molecular Formula
C25H34N6O8S2
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Molecular Weight
610.7
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Smiles
CC1=CC=CC(/C=N/NC2=CC(N3CCOCC3)=NC(OCCC4=CC=CC=N4)=N2)=C1.CS(=O)(O)=O.CS(=O)(O)=O
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Target
Interleukin Related; PIKfyve
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Isoform
IL-12; IL-23; IL-4; IL-5; IL-8
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Purity
99.83
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Solubility
DMSO : 12.5 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H315, H319, H335
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Precautions
H315, H319, H335
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Apilimod (mesylate) [CAS 870087-36-8]
Apilimod (mesylate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.