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Aromatase-IN-3

Aromatase-IN-3

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SKU:QM-0073477

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  • Description

    Aromatase-IN-3 (compound 7d) is an aromatase inhibitor with an IC50 of 54 nM. Through suppressing the conversion of androstenedione to oestrogen caused by aromatase, Aromatase-IN-3 exerts an appreciable tumor growth inhibitory activities against breast cancer cell lines, suggesting its usage for ER+ cancer research[1].

  • Molecular Formula

    C38H38N2O3

  • Molecular Weight

    570.72

  • Smiles

    O=C(C(OCC)=O)C1=CN(CCCCCNC2=CC=C(/C(C3=CC=CC=C3)=C(C4=CC=CC=C4)\C)C=C2)C5=C1C=CC=C5

  • Target

    Cytochrome P450

  • Isoform

    Aromatase/CYP19A1

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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Aromatase-IN-3

Aromatase-IN-3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.