Asiatic acid [CAS 464-92-6]
Asiatic acid [CAS 464-92-6]
SKU:QM-0162227-01
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Product Details
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Description
Asiatic acid, a pentacyclic triterpene found in Centella asiatica (Centella asiatica), has anticancer activity. Asiatic acid induces apoptosis in melanoma cells and has barrier protective effects on human aortic endothelial cells (HAEC) . Asiatic acid also has anti-inflammatory activity and inhibits tumor necrosis factor (TNF) -α-induced endothelial barrier dysfunction. Asiatic acid also inhibits NLRP3 inflammasome activation and NF-κB pathway, effectively inhibits inflammation in rats, and has neuroprotective effects in rat spinal cord injury (SCI) model[1][2][3][4][5].
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CAS Number
[464-92-6]
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Molecular Formula
C30H48O5
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Molecular Weight
488.7
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Smiles
C[C@@]1(CO)[C@@H](O)[C@H](O)C[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@](C(O)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H]
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Target
Apoptosis; Parasite
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Concentration
10mM
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Purity
99.49
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Solubility
DMSO : 250 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, protect from light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Asiatic acid [CAS 464-92-6]
Asiatic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.