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AT9283 (lactic acid) [CAS 896466-76-5]
AT9283 (lactic acid) [CAS 896466-76-5]
SKU:QM-0056903
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Product Details
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Description
AT9283 lactic acid is a multi-targeted kinase inhibitor with potent activity against Aurora A/B, JAK2/3, Abl (T315I) and Flt3 (IC50s ranging from 1 to 30 nM) . AT9283 lactic acid inhibits growth and survival of multiple solid tumors in vitro and in vivo[1][2].
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CAS Number
[896466-76-5]
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Molecular Formula
C22H29N7O5
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Molecular Weight
471.51
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Smiles
O=C(NC1CC1)NC2=CNN=C2C3=NC(C=C4)=C(C=C4CN5CCOCC5)N3.O=C(O)[C@H](C)O
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Target
Apoptosis; Aurora Kinase; Autophagy; Bcr-Abl; FLT3; JAK
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Isoform
Abl; Aurora A; Aurora B; JAK2; JAK3
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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AT9283 (lactic acid) [CAS 896466-76-5]
AT9283 (lactic acid) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.