Auristatin F-d8
Auristatin F-d8
SKU:QM-0072071
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Product Details
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Description
Auristatin F-d8 is deuterium labeled Auristatin F. Auristatin F is a potent cytotoxin in antibo-conjugated agents and an analogue of MMAF. Auristatin F is a potent microtubule inhibitor and vascular damaging agent (VDA). Auristatin F inhibits cell division by preventing tubulin aggregation.Auristatin F can be used in antibody-drug conjugates (ADC).
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Molecular Formula
C40H59D8N5O8
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Molecular Weight
754.04
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Smiles
CC([C@@H](C(N[C@@]([2H])(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])C(N(C)[C@H]([C@H](OC)CC(N1CCC[C@]1([C@@H]([C@H](C(N[C@@H](CC2=CC=CC=C2)C(O)=O)=O)C)OC)[H])=O)[C@H](CC)C)=O)=O)N(C)C)C
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Target
ADC Payload; Isotope-Labeled Compounds; Microtubule/Tubulin
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Purity
99.82
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Hazard Statement
H300+H330, H340, H360, H370, H372, H412
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Precautions
H300+H330, H340, H360, H370, H372, H412
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Auristatin F-d8
Auristatin F-d8 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.