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Aurothioglucose [CAS 12192-57-3]
Aurothioglucose [CAS 12192-57-3]
SKU:QM-0157173-01
£361.04 GBP
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Product Details
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Description
Aurothioglucose (Gold thioglucose), containing monovalent gold ion, is a potent active-site inhibitor of TrxR1 (thioredoxin reductase 1), with an IC50 of 65 nM. Aurothioglucose inhibits the DNA binding of NF-κB in vitro. Aurothioglucose shows anti-HIV and anti-rheumatic activities[1][2].
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CAS Number
[12192-57-3]
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Molecular Formula
C6H11AuO5S
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Molecular Weight
392.18
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Smiles
O[C@@H]1[C@](O[Au+][SH-]2)([H])C2O[C@H](CO)[C@H]1O
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Target
HIV; NF-κB; Reactive Oxygen Species (ROS)
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Concentration
10mM
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Purity
96.1
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Solubility
DMSO : 6 mg/mL (ultrasonic) |H2O : 125 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H317, H334
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Precautions
H317, H334
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Aurothioglucose [CAS 12192-57-3]
Aurothioglucose is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.