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Avatrombopag (hydrochloride) [CAS 570403-17-7]

Avatrombopag (hydrochloride) [CAS 570403-17-7]

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SKU:QM-0144798-01

£111.63 GBP
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  • Description

    Avatrombopag (AKR-501) hydrochloride is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM) . Avatrombopag hydrochloride mimics the biological activities of TPO. Avatrombopag hydrochloride increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag hydrochloride is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A[1][2][3].

  • CAS Number

    [570403-17-7]

  • Molecular Formula

    C29H35Cl3N6O3S2

  • Molecular Weight

    686.12

  • Smiles

    O=C(C1CCN(C2=NC=C(C(NC3=NC(C4=CC(Cl)=CS4)=C(N5CCN(C6CCCCC6)CC5)S3)=O)C=C2Cl)CC1)O.Cl

  • Target

    Thrombopoietin Receptor

  • Purity

    97.05

  • Solubility

    DMSO : 8.33 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Room Temperature

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Variant Variant total Quantity Price Variant total
1 mgQM-0144798-01
1 mgQM-0144798-01
£111.63/ea
£0.00
£111.63/ea £0.00
5 mgQM-0144798-02
5 mgQM-0144798-02
£238.32/ea
£0.00
£238.32/ea £0.00
10 mM - 1 mLQM-0144798-03
10 mM - 1 mLQM-0144798-03
£333.10/ea
£0.00
£333.10/ea £0.00
10 mgQM-0144798-04
10 mgQM-0144798-04
£351.32/ea
£0.00
£351.32/ea £0.00
50 mgQM-0144798-05
50 mgQM-0144798-05
£916.29/ea
£0.00
£916.29/ea £0.00
100 mgQM-0144798-06
100 mgQM-0144798-06
£1,267.43/ea
£0.00
£1,267.43/ea £0.00
250 mgQM-0144798-07
250 mgQM-0144798-07
£1,882.22/ea
£0.00
£1,882.22/ea £0.00
500 mgQM-0144798-08
500 mgQM-0144798-08
£2,685.34/ea
£0.00
£2,685.34/ea £0.00
1 gQM-0144798-09
1 gQM-0144798-09
£3,777.62/ea
£0.00
£3,777.62/ea £0.00

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Avatrombopag (hydrochloride) [CAS 570403-17-7]

Avatrombopag (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.