Azvudine (hydrochloride) [CAS 1333126-31-0]
Azvudine (hydrochloride) [CAS 1333126-31-0]
SKU:QM-0155255-01
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Product Details
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Description
Azvudine (RO-0622) hydrochloride is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine hydrochloride exerts highly potent inhibition on HIV-1 (EC50s ranging from 0.03 to 6.92 nM) and HIV-2 (EC50s ranging from 0.018 to 0.025 nM) . Azvudine hydrochloride inhibits NRTI-resistant viral strains[1]. Azvudine (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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CAS Number
[1333126-31-0]
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Molecular Formula
C9H12ClFN6O4
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Molecular Weight
322.68
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Smiles
O[C@@H]1[C@](CO)(N=[N+]=[N-])O[C@@H](N2C(N=C(N)C=C2)=O)[C@H]1F.Cl
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Target
HBV; HCV; HIV; Reverse Transcriptase
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Isoform
HIV-1; HIV-2
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Purity
99.19
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Solubility
DMSO : 25 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Azvudine (hydrochloride) [CAS 1333126-31-0]
Azvudine (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.