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Barasertib (dihydrochloride) [CAS 722543-50-2]
Barasertib (dihydrochloride) [CAS 722543-50-2]
SKU:QM-0081108
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Product Details
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Description
Barasertib (AZD1152 dihydrochloride), a pro-drug of Barasertib-hQPA, is a highly selective Aurora B inhibitor with an IC50 of 0.37 nM in a cell-free assay. Barasertib (AZD1152 dihydrochloride) induces growth arrest and apoptosis in cancer cells[1].
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CAS Number
[722543-50-2]
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Molecular Formula
C26H33Cl2FN7O6P
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Molecular Weight
660.46
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Smiles
O=C(CC1=NNC(NC2=C3C=CC(OCCCN(CCOP(O)(O)=O)CC)=CC3=NC=N2)=C1)NC4=CC(F)=CC=C4.Cl.Cl
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Target
Apoptosis; Aurora Kinase
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Barasertib (dihydrochloride) [CAS 722543-50-2]
Barasertib (dihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.