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BChE/p38-α MAPK-IN-2
BChE/p38-α MAPK-IN-2
SKU:QM-0015207
Price on request
Quantity
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Product Details
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Description
BChE/p38-α MAPK-IN-2 is a BChE and p38-α MAPK dual inhibitor. BChE/p38-α MAPK-IN-2 inhibits hBChE with an IC50 of 5.1 nM, showing 1000-fold selectivity over hAChE. BChE/p38-α MAPK-IN-2 inhibits p38α MAPK with an IC50 of 8.12 μM. BChE/p38-α MAPK-IN-2 exhibits neuroprotective effect and can be used for the research of neurological disease, such as Alzheimer’s disease[1].
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Molecular Formula
C27H33N5O4
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Molecular Weight
491.58
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Smiles
CC(NCC(NCC1=CC=CC(N2N=C(C=C2OC(N(CC3=CC=CC=C3)C)=O)C(C)(C)C)=C1)=O)=O
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Target
Cholinesterase (ChE) ; p38 MAPK
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Isoform
AChE; BChE
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Shipping Conditions
Room temperature
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BChE/p38-α MAPK-IN-2
BChE/p38-α MAPK-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.