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Bicuculline (methobromide) [CAS 66016-70-4]

Bicuculline (methobromide) [CAS 66016-70-4]

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SKU:QM-0056950

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  • Description

    Bicuculline methobromide is a selective GABAA Receptor antagonist with an IC50 value of 3 μM. Bicuculline methobromide induces clonic tonic convulsions in mammals and can also be used to block Ca2+ activated potassium channels. Bicuculline methobromide can be used in studies of epilepsy and other related psychiatric disorders[1][2].

  • CAS Number

    [66016-70-4]

  • Molecular Formula

    C21H20BrNO6

  • Molecular Weight

    462.29

  • Smiles

    C[N+]1([C@](C2=C(CC1)C=C3C(OCO3)=C2)([H])[C@@]4([H])C5=C(C6=C(OCO6)C=C5)C(O4)=O)C.[Br-]

  • Target

    GABA Receptor

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

  • Hazard Statement

    H300-H311+H331-H410

  • Precautions

    P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P361+P364-P391-P403+P233-P405-P501

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Bicuculline (methobromide) [CAS 66016-70-4]

Bicuculline (methobromide) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.