Bicuculline (methochloride) [CAS 38641-83-7]
Bicuculline (methochloride) [CAS 38641-83-7]
SKU:QM-0146087-01
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Product Details
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Description
Bicuculline ((+) -Bicuculline; d-Bicuculline) methochloride is a selective GABAA receptor antagonist with an IC50 value of 3 μM. Bicuculline methochloride induces clonic tonic convulsions in mammals and can also be used to block Ca2+ activated potassium channels. Bicuculline methochloride can be used in studies of epilepsy and other related psychiatric disorders[1][2].
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CAS Number
[38641-83-7]
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Molecular Formula
C21H20ClNO6
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Molecular Weight
417.84
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Smiles
C[N+]([C@](C1=C2C=C3C(OCO3)=C1)([H])[C@@](O4)([H])C(C=CC5=C6OCO5)=C6C4=O)(CC2)C.[Cl-]
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Target
GABA Receptor
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Purity
99.8
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Solubility
H2O : 50 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Bicuculline (methochloride) [CAS 38641-83-7]
Bicuculline (methochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.