Bomedemstat (hydrochloride)
Bomedemstat (hydrochloride)
SKU:QM-0136464-01
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Product Details
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Description
Bomedemstat (IMG-7289) hydrochloride is an orally active and irreversible lysine-specific demethylase 1 (LSD1) inhibitor. Bomedemstat hydrochloride can increase H3K4 and H3K9 methylation, and then alter gene expression. Bomedemstat hydrochloride shows anti-cancer activities, inhibits cancer cell proliferation and induces apoptosis[1][2].
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Molecular Formula
C28H35ClFN7O2
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Molecular Weight
556.07
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Smiles
O=C(N1CCN(CC1)C)[C@@H](NC(C2=CC=C(N3C=CN=N3)C=C2)=O)CCCN[C@H]4[C@@](C5=CC=C(C=C5)F)([H])C4.[H]Cl
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Target
Apoptosis; Histone Demethylase
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Isoform
KDM1/LSD1
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Purity
99.94
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Solubility
DMSO : 75 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Bomedemstat (hydrochloride)
Bomedemstat (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.