Braco-19 (trihydrochloride) [CAS 1177798-88-7]
Braco-19 (trihydrochloride) [CAS 1177798-88-7]
SKU:QM-0151651-01
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Product Details
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Description
Braco-19 trihydrochloride is a potent telomerase/telomere inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor[1][2].
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CAS Number
[1177798-88-7]
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Molecular Formula
C35H46Cl3N7O2
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Molecular Weight
703.14
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Smiles
CN(C1=CC=C(NC2=C(C=CC(NC(CCN3CCCC3)=O)=C4)C4=NC5=CC(NC(CCN6CCCC6)=O)=CC=C52)C=C1)C.Cl.Cl.Cl
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Target
CMV; DNA/RNA Synthesis
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Purity
99.57
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Solubility
H2O : 22 mg/mL (ultrasonic; warming) |DMSO : 50 mg/mL (ultrasonic; warming; heat to 80°C)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H301
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Precautions
H301
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Braco-19 (trihydrochloride) [CAS 1177798-88-7]
Braco-19 (trihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.