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BRAF V600E/CRAF-IN-2 [CAS 2499499-62-4]
BRAF V600E/CRAF-IN-2 [CAS 2499499-62-4]
SKU:QM-0066875
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Product Details
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Description
BRAF V600E/CRAF-IN-2 (Compound 9c) is a potent inhibitor of BRAF V600E/CRAF with IC50s of 0.888 and 0.229 μM, respectively. BRAF V600E/CRAF-IN-2 triggers apoptosis and cell cycle arrest at G0/G1 phase in HCT-116 colon cancer cell. BRAF V600E/CRAF-IN-2 has the potential for the research of cancer diseases[1].
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CAS Number
[2499499-62-4]
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Molecular Formula
C30H30F3N5O2
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Molecular Weight
549.59
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Smiles
CCN1CCN(CC1)C2=CC(C(F)(F)F)=CC(C(NC3=CC=CC(NC4=NC5=CC=CC(OC)=C5C=C4)=C3)=O)=C2
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Target
Raf
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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BRAF V600E/CRAF-IN-2 [CAS 2499499-62-4]
BRAF V600E/CRAF-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.