Bryostatin 1 [CAS 83314-01-6]
Bryostatin 1 [CAS 83314-01-6]
SKU:QM-0057493
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Product Details
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Description
Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a potent and central nervous system (CNS) -permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein with Kis of 8.07 nM and 0.45 nM, respectively. Bryostatin 1 has anti-cancer, anti-inflammatory, neuroprotective, anti-HIV-1 infection properties[1][2][3][4].
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CAS Number
[83314-01-6]
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Molecular Formula
C47H68O17
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Molecular Weight
905.03
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Smiles
O[C@]12[C@H](/C(C[C@](C[C@](OC(C[C@@H](C[C@@]3([H])O[C@](O)(C(C)([C@@H](OC(C)=O)C3)C)C[C@@](C/4)([H])O[C@@](CC4=C/C(OC)=O)([H])/C=C/C2(C)C)O)=O)([H])[C@H](O)C)([H])O1)=C/C(OC)=O)OC(/C=C/C=C/CCC)=O
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Target
Bacterial; HIV; PKC
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Isoform
HIV-1
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Purity
99.7
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Solubility
DMSO : 50 mg/mL (ultrasonic; warming)
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Hazard Statement
H315, H319, H335, H373
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Precautions
H315, H319, H335, H373
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Bryostatin 1 [CAS 83314-01-6]
Bryostatin 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.