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BU224 (hydrochloride) [CAS 205437-64-5]

BU224 (hydrochloride) [CAS 205437-64-5]

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QM-0081013-01

£92.50 GBP
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Product Details

  • Description

    BU224 hydrochloride is a selective and high affinity imidazoline I2 receptor ligand, with a Ki of 2.1 nM. BU224 hydrochloride is sometimes used as an I2 receptor antagonist. BU224 hydrochloride exerts neuroprotective effects, with anti-inflammatory and anti-apoptotic properties. BU224 hydrochloride improves memory in 5XFAD mice, enlarging dendritic spines and reducing Aβ-induced changes in NMDARs. BU224 hydrochloride can be used for Alzheimer's disease research[1][2][3].

  • CAS Number

    [205437-64-5]

  • Molecular Formula

    C12H12ClN3

  • Molecular Weight

    233.7

  • Smiles

    C1(C2=NCCN2)=NC3=CC=CC=C3C=C1.Cl

  • Target

    Apoptosis; Imidazoline Receptor; TNF Receptor

  • Isoform

    TNFRSF5/CD40

  • Purity

    96.96

  • Solubility

    DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    4°C (Powder, protect from light)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319

  • Precautions

    H302, H315, H319
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Variant Variant total Quantity Price Variant total
5 mgQM-0081013-01
5 mgQM-0081013-01
£92.50/ea		 £0.00
£92.50/ea £0.00
10 mgQM-0081013-02
10 mgQM-0081013-02
£127.38/ea		 £0.00
£127.38/ea £0.00
25 mgQM-0081013-03
25 mgQM-0081013-03
£288.14/ea		 £0.00
£288.14/ea £0.00
50 mgQM-0081013-04
50 mgQM-0081013-04
£432.73/ea		 £0.00
£432.73/ea £0.00
100 mgQM-0081013-05
100 mgQM-0081013-05
£602.83/ea		 £0.00
£602.83/ea £0.00
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BU224 (hydrochloride) [CAS 205437-64-5]

BU224 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.