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BWA-522 intermediate-1 [CAS 2241315-66-0]
BWA-522 intermediate-1 [CAS 2241315-66-0]
SKU:QM-0202625-01
£36.91 GBP
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Product Details
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Description
BWA-522 intermediate-1 is an intermediate in the synthesis of PROTAC BWA-522 and serves as a ligand molecule for cereblon E3 ubiquitin ligase. BWA-522 is an orally active small molecule protein-targeting chimera (PROTAC) that has significant degradation effects on AR-FL and AR-V7[1].
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CAS Number
[2241315-66-0]
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Molecular Formula
C19H19N3O5
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Molecular Weight
369.37
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Smiles
O=CC1CCN(C2=CC3=C(C(N(C(CC4)C(NC4=O)=O)C3=O)=O)C=C2)CC1
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Target
Ligands for E3 Ligase
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Isoform
Cereblon
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Purity
99.27
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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BWA-522 intermediate-1 [CAS 2241315-66-0]
BWA-522 intermediate-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.