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C-Met/HDAC-IN-2 [CAS 2740495-53-6]
C-Met/HDAC-IN-2 [CAS 2740495-53-6]
SKU:QM-0065331
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Product Details
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Description
C-Met/HDAC-IN-2 is a highly potent c-Met and HDAC dual inhibitor with IC50s of 18.49 nM and 5.40 nM for HDAC1 and c-Met, respectively. c-Met/HDAC-IN-2 has antiproliferative activities against certain cancer cell lines. c-Met/HDAC-IN-2 can cause G2/M-phase arrest and induce apoptosis in HCT-116. c-Met/HDAC-IN-2 can be used for researching anti-cancer resistance[1].
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CAS Number
[2740495-53-6]
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Molecular Formula
C34H33N5O7
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Molecular Weight
623.66
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Smiles
O=C(C1=NN(C2=CC=CC=C2)C=CC1=O)NC3=CC=C(OC4=CC=NC5=CC(OCCCCCCC(NO)=O)=C(OC)C=C45)C=C3
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Target
Apoptosis; c-Met/HGFR; HDAC
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Isoform
HDAC1
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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C-Met/HDAC-IN-2 [CAS 2740495-53-6]
C-Met/HDAC-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.