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CA IX/VEGFR-2-IN-2
CA IX/VEGFR-2-IN-2
SKU:QM-0107321
Price on request
Quantity
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Product Details
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Description
CA IX/VEGFR-2-IN-2 (compound 5e) is a dual-targeted inhibitor. CA IX/VEGFR-2-IN-2 shows strong inhibitory effects on both CA IX (Ki=3.1 μM) and VEGFR-2 (IC50=32.1 nM) . CA IX/VEGFR-2-IN-2 can be used for the study of pancreatic (PANC1), breast cancer (MCF7) and prostate cancer (PC3) [1].
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Molecular Formula
C22H18FN3O3S
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Molecular Weight
423.46
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Smiles
O=C1C(/C(C)=N/NC2=NC(C3=CC=C(F)C=C3)=CS2)=CC4=C(O1)C(OCC)=CC=C4
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Target
Bcl-2 Family; Carbonic Anhydrase; Caspase; Cytochrome P450; MDM-2/p53; Reactive Oxygen Species (ROS) ; VEGFR
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Isoform
CA IX; VEGFR2/KDR/Flk-1
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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CA IX/VEGFR-2-IN-2
CA IX/VEGFR-2-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.