CA IX/VEGFR-2-IN-3
CA IX/VEGFR-2-IN-3
SKU:QM-0009413
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Product Details
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Description
CA IX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. CA IX/VEGFR-2-IN-3 exhibits anticancer activity, inhibiting the growth of MCF-7 breast cancer cells (with an IC50 of 22.33 μM) and mouse fibroblast cell line 3T3 (where cell viability is less than 40% at a concentration of 100 μM) . CA IX/VEGFR-2-IN-3 can be used for research in the field of cancer treatment[1].
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Molecular Formula
C19H16ClN3O5S2
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Molecular Weight
465.93
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Smiles
O=C(NC1=CC=C(C)C(S(=O)(N)=O)=C1)CN(C/2=O)C(SC2=C/C3=CC=C(Cl)C=C3)=O
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Target
Carbonic Anhydrase; VEGFR
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Isoform
CA II; VEGFR2/KDR/Flk-1
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Shipping Conditions
Room temperature
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CA IX/VEGFR-2-IN-3
CA IX/VEGFR-2-IN-3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.