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Cabamiquine (succinate) [CAS 2444781-71-7]
Cabamiquine (succinate) [CAS 2444781-71-7]
SKU:QM-0139225-01
£129.63 GBP
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Product Details
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Description
Cabamiquine (DDD107498) succinate is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite, with an EC50 of 1 nM against P. falciparum 3D7. Cabamiquine succinate inhibits protein synthesis by targeting eEF2/CaMKIII, with an EC50 of 2 nM for WT-PfeEF2[1].
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CAS Number
[2444781-71-7]
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Molecular Formula
C31H37FN4O6
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Molecular Weight
580.65
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Smiles
OC(CCC(O)=O)=O.O=C(C1=CC(C2=CC=C(C=C2)CN3CCOCC3)=NC4=CC=C(C=C41)F)NCCN5CCCC5
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Target
CaMK; Parasite
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Isoform
Plasmodium
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Purity
99.8
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Solubility
DMSO : 135 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Room Temperature
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Cabamiquine (succinate) [CAS 2444781-71-7]
Cabamiquine (succinate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.