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Carboxylesterase-IN-2 [CAS 2764748-88-9]
Carboxylesterase-IN-2 [CAS 2764748-88-9]
SKU:QM-0147825-01
£414.50 GBP
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Product Details
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Description
Carboxylesterase-IN-2 (compound 4u) is a potent inhibitor of Carboxylesterase Notum with an IC50 less than or equal to 10 nM. Notum is a negative regulator of Wnt signaling acting through the hydrolysis of a palmitoleoylate ester, which is required for Wnt activity. Carboxylesterase-IN-2 has the potential for the research of cancer disease[1].
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CAS Number
[2764748-88-9]
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Molecular Formula
C13H12N4OS
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Molecular Weight
272.33
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Smiles
O=C1NN=C2C=CC(SC3=CC=C(C)C(C)=C3)=NN21
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Target
Carboxylesterase (CES) ; Wnt
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Concentration
10mM
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Purity
99.91
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Solubility
DMSO : 50 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Carboxylesterase-IN-2 [CAS 2764748-88-9]
Carboxylesterase-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.