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CDK4/6/HDAC-IN-1
CDK4/6/HDAC-IN-1
SKU:QM-0009477
Price on request
Quantity
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Product Details
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Description
CDK4/6/HDAC-IN-1 (Compound N14) is a dual-targeting inhibitor of CDK4/6 and HDAC (IC50: CDK4 = 7.23 nM, CDK6 = 13.20 nM, HDAC1 = 55.66 nM, HDAC6 = 48.38 nM) . CDK4/6/HDAC-IN-1 induces cell Apoptosis and G0/G1 phase arrest through HDAC-p21-CDK signaling pathway. CDK4/6/HDAC-IN-1 inhibits hepatocellular carcinoma[1].
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Molecular Formula
C35H39N9O5
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Molecular Weight
665.74
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Smiles
O=C(NO)/C=C/C1=CC=C(NC(CN2CCN(C3=CC=C(NC4=NC=C5C(N(C6CCCC6)C(C(C(C)=O)=C5C)=O)=N4)N=C3)CC2)=O)C=C1
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Target
Apoptosis; CDK; HDAC
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Isoform
CDK1; CDK4; CDK6
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Shipping Conditions
Room temperature
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CDK4/6/HDAC-IN-1
CDK4/6/HDAC-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.