Cephaeline (Standard) [CAS 483-17-0]
Cephaeline (Standard) [CAS 483-17-0]
SKU:QM-0024294
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Product Details
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Description
Cephaeline ((-) -Cephaeline), a desmethyl analog of Emetine, is a phenolic alkaloid in Indian Ipecac roots isolated from the Cephaelis ipecacuanha. Cephaeline exhibits potent inhibition of both Zika virus (ZIKV) and Ebola virus (EBOV) infections. Cephaeline is an inductor of histone H3 acetylation and an inhibitor of mucoepidermoid carcinoma cancer stem cells (MEC), which promotes ferroptosis by inhibiting NRF2 to exert anti-lung cancer efficacy[1][2][3][4].
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CAS Number
[483-17-0]
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Molecular Formula
C28H38N2O4
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Molecular Weight
466.61
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Smiles
OC1=CC2=C([C@@H](C[C@@H]3[C@@H](CC)CN4CCC5=CC(OC)=C(OC)C=C5[C@]4([H])C3)NCC2)C=C1OC
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Target
Ferroptosis; Filovirus; Flavivirus; Keap1-Nrf2; Reactive Oxygen Species (ROS)
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Shipping Conditions
Room temperature
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Cephaeline (Standard) [CAS 483-17-0]
Cephaeline (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.